Tag Archives: niddm diabetes

Pathogenesis of NIDDM ( Non insulin dependent diabetes )

NIDDM

Pathogenesis of NIDDM (NIDDM) is caused by an imbalance between insulin sensitivity and insulin secretion. Both longitudinal and cross-sectional studies have shown that early abnormalities that can be detected in NIDDM are impaired in the body’s ability to respond to insulin. Because the pancreas is able to increase insulin secretion appropriately to offset insulin resistance, glucose tolerance remains normal. However, over time, a beta cell fails to maintain high insulin secretion rate, and relative insulin deficiency (ie, […]

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